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SEP 08  

 

Sat Sep 6, 10:23 PM ET

VietNamNet Bridge - The provision of accurate information regarding avian influenza will help the government make correct decisions in preventing and controlling the disease, said a workshop in Hanoi. (VIETNAM) (BIRD FLU)

 

Accurate information helps reduce losses from bird flu

 

Sat Sep 6, 10:23 PM ET

 

Addressing the opening ceremony of a two-day workshop for journalists on Sept. 4, the Rector of the Hanoi School of Public Health (HSPH), Le Vu Anh, said that economic losses caused by bird flu outbreaks in Vietnam constituted one percent of the country's gross domestic product (GDP).

 

The US Deputy Chief of Mission , Virgina E. Palmer, praised Vietnam for its achievements in bird flu prevention and control, which has set an example for other countries to follow.

 

As one of the first of the 61 countries reporting an outbreak of the H5N1 bird flu virus in poultry, Vietnam experienced four major outbreaks between Dec. 2003 and Aug. 2008, with 106 reported human cases, 52 of which were fatal.

 

According to the Head of the Preventive Medicine Department of the Health Ministry, Nguyen Huy Nga, Vietnam is one of the nations facing a high risk of bird flu re-emergence, as 97 percent of those infected were exposed directly or indirectly to the virus. However, he confirmed that there is no evidence of human-to-human H5N1 transmission in Vietnam .

 

At the workshop entitled "Getting the story", jointly held by the HSPH and the US Embassy in Hanoi , participants discussed challenges to bird flu prevention and control in Vietnam , such as clamping down on the smuggling of poultry and the lack of knowledge amongst vets in dealing with the virus.

 

There is currently no effective bird flu vaccine for humans, and one of the conclusions arising from the workshop is that more effective measures should be in place to prevent the spread of the disease from wild animals and migrating birds.

 

(Source: VNA)

Indonesian Health Minister Siti Fadilah Supari (right, in blue) sets slaughtered poultry on fire during a mass culling operation in Jakarta, in January 2007. With nearly half the world's human bird flu deaths, concern is building over Indonesia's refusal to share virus samples and its health minister's increasingly strident denunciations of global 'conspiracies'. Photo:Adek Berry/AFP (INDONESIA) (BIRD FLU)

 

Alarm as Indonesia thumbs nose at West over bird flu

 

Sun Sep 7, 12:47 AM ET

 

JAKARTA (AFP) - With nearly half the world's human bird flu deaths, concern is building over Indonesia's refusal to share virus samples and its health minister's increasingly strident denunciations of global "conspiracies".

 

 

Indonesia stopped sharing the samples with the World Health Organisation (WHO) in December 2006 on fears pharmaceutical companies would use them to make vaccines that are too expensive for poor countries.

 

The initial move by Health Minister Siti Fadilah Supari earned international plaudits for taking on an unfair global system, but with WHO negotiations at an impasse, Supari's increasing belligerence is raising alarm.

 

The minister has broadened her critique of an "unfair, neocolonialist" global health system, raising the possibility earlier this year the United States was using the virus to develop biological weapons in her book "It's Time for the World to Change: Divine Hands Behind Avian Influenza."

 

Supari told a rapturous crowd at a book discussion last week that rich nations were creating "new viruses" and sending them to developing nations in order create markets for drug companies to sell vaccines.

 

"Indonesia sends a virus to the WHO but it suddenly it ends up with the US government. Then the US government turns the virus into dollars and we don't know what kind of research," Supari said.

 

"Then the virus is turned into vaccines (that are sent to) Indonesia and Indonesia has to buy them and if they don't buy them, it turns and turns again, and in the end developed countries make new viruses which are then sent to developing countries," she said.

 

"The conspiracy between superpower nations and global organisations isn't a theory, isn't rhetoric, but it's something I've experienced myself."

 

Bird flu scientists abroad and in Indonesia have raised concerns that while Supari seeks to reshape the global order, time is being wasted in understanding a virus that could potentially kill millions if it mutates into a form transmissible between humans.

 

Indonesia announced in August that 112 people have died from the virus, out of more than 240 worldwide since late 2003. Only a handful of samples and genetic sequences have been shared with the WHO and researchers.

 

The health ministry also earlier this year stopped publicly announcing bird flu deaths, only releasing information information weeks or months after victims have died.

 

"I'm a bit suspicious what she's doing is more politics and not in fact for the global health system," said Ngurah Mahardika, a virologist from Udayana University on Bali island.

 

"This will lessen the strength, the power of the preparedness of the global system ... (withholding samples means) we don't have any epidemiological and virological signal now of what the virus looks like," Mahardika said.

 

"This is really increasing our pandemic risk (because) we don't know about any signals of a pandemic."

 

While Supari has insisted Indonesia and other developing countries can stand on their own in researching the virus, Indonesian scientists say they too have been shut out from access to flu samples.

 

"The minister of health is keeping the virus in the laboratories but they are giving no access to Indonesian scientists at the moment," said Amin Subandrio, the head of the national bird flu committee's expert panel.

 

Subandrio, who has supported Supari in trying to extract a change in WHO rules to allow developing nations to secure supply of and revenue from vaccines taken from their virus strains, said withholding samples was nonetheless risky.

 

He said Supari's claim of a Western-led global conspiracy was not backed by evidence.

 

"I really cannot explain it 100 percent, but probably she received the wrong information from the wrong person," he said.

 

But while scientists and global health authorities express worry, Supari continues to enjoy popularity at home.

 

Her book has entered into multiple print runs in Indonesian and English and plans have reportedly been made for a film adaptation. Mainstream academics have also rallied to her side.

 

"I believe she represents a kind of minister or politician who has a very clear political standing," political scientist Bima Arya Sugiarto said.

 

President Susilo Bambang Yudhoyono has distanced himself from Supari's more controversial comments but has made no sign of moving her from her post.

 

"In Indonesia we recognise that there are issues to be resolved in the world health system but certainly we don't believe in conspiracy theories," presidential spokesman Dino Patti Djalal said.

 

by Aubrey Belford

Sun Sep 7, 8:53 PM ET

With no reports of bird flu cases close to the last three months in the country, India is considering an approach to the France-based Organisation for Animal Health (OIA) for according it 'the avian influenza free country' soon. (INDIA) (BIRD FLU)

 

India may approach OIA due to no bird flu report

 

Sun Sep 7, 8:53 PM ET

 

With no reports of bird flu cases close to the last three months in the country, India is considering an approach to the France-based Organisation for Animal Health (OIA) for according it 'the avian influenza free country' soon.

 

Besides, India and neighbouring Bangladesh have set up a joint mechanism through a series of meeting held amongst officials to share and monitor information on bird flu cases in the poultry industry.

 

India has been maintaining that the virus came from Bangladesh through the illegal poultry trade.

 

Even agriculture minister Sharad Pawar had supported this view.

 

The animal husbandry department under the ministry of agriculture, in February 2008, had made a formal request to the Bangladesh government through the ministry of external affairs to share the genetic history of its virus.

 

After much deliberation, Bangladesh shared data on the genetic make up of the H5N1 virus strain, which had been found 'similar' to the bird flu virus and had caused India's worst Avian Influenza outbreak earlier this year.

 

"Bangladesh has been proactive and most forth coming in sharing information," an official with the animal husbandry department told FE.

 

India and Bangladesh share a 4,095-kilometre border.

 

India had reported its first case of bird flu in Maharashtra back in 2006 but later that year declared itself 'bird-flu free'.

 

However, the country has suffered two more outbreaks since then, the latest and worst being in West Bengal, where it erupted earlier this year.

 

According to OIA, the avian influenza-free country status is given if a nation reports no outbreak of bird flu for a stretch of three months from the time it completes disinfection and clean-up of the previous outbreak site.

 

"We are closely monitoring the situation, and will approach OIA soon," the official said.

 

The country produces more than 2.0 million tonne of broiler chickens annually and is the fifth largest producer in the world.

 

The country is the largest producer of eggs, with a production of around 44 billion pieces.

 

The Rs 40,000-crore domestic poultry industry provides direct and indirect employment to more than 2 million people.

 

Mon Sep 8, 10:24 AM ET

In order to eradicate bird flu at the grassroots, Nasarawa State government has involved traditional rulers, women groups and community leaders in the fight against the disease. (NIGERIA) (BIRD FLU)

 

Nigeria: Nasarawa Seeks Support of Community Leaders Over Bird Flu

 

Mon Sep 8, 10:24 AM ET

 

In order to eradicate bird flu at the grassroots, Nasarawa State government has involved traditional rulers, women groups and community leaders in the fight against the disease.

 

This was disclosed to newsmen in Lafia by the Avian Influenza Control Project Communication Desk Officer, Mallam Abubakar Tanko.

 

He said the involment of community leaders and other interest groups was to ensure that the disease was reduced to minimal level, adding that students and pupils were also involved in order to carry everyone along in the fight

 

He said that through the local government desk offices and the three components of animal, human and community health, the project confrontating the disease through continuos disinfection .

 

He explained that the personnel were now concentrating on affected communities, bird markets and pockets of reported outbreaks.

 

The officer also said that women groups, traditional opinion, religious and community leaders were being sensitised on the dangers of the disease and the need for them to report suspected cases to the appropriate organs.

 

He commended the desk officers in the fight against the disease and urged them not to relent in their efforts.

 

He also appreciated the determination of the state government in the fight especially in meeting all the logistical needs of the project and called on local government administrators to also give more support to the project.

Tue Sep 9, 5:58 PM ET

A file photo of a bird vendor on his way to a Buddhist pagoda in Vientiane. Laos. Authorities in Laos detected a fresh outbreak of bird flu in the north of the country last week and slaughtered all poultry affected, a government spokesman says. "We have killed all of the poultry within a kilometre radius - about 7,000 of them," and a quarantine zone has been set up on the area's perimeter, foreign ministry spokesman Yong Chanthalangsy told AFP. (BIRD FLU) (LAOS)

 

Bird flu found in northern Laos

 

Tue Sep 9, 5:58 PM ET

 

Authorities in Laos detected a fresh outbreak of bird flu in the north of the country last week and slaughtered all poultry affected, a government spokesman says.

 

The government did not say how many birds were infected with the deadly virus, which was detected in a village about 150km north of the ancient royal capital Luang Prabang, a UNESCO World Heritage site.

 

"We have killed all of the poultry within a kilometre radius - about 7,000 of them," and a quarantine zone has been set up on the area's perimeter, foreign ministry spokesman Yong Chanthalangsy told AFP.

 

No human infections were suspected, he said.

 

Two people have died of bird flu in communist-ruled Laos since 2003, when the virus resurfaced in Southeast Asia, according to World Health Organisation (WHO) statistics. Both deaths were reported last year.

 

The WHO says 243 people have died from bird flu worldwide. The H5N1 avian influenza virus mainly kills birds but scientists fear it could mutate to easily jump from human to human, sparking a global pandemic.

Tue Sep 9, 6:18 PM ET

LOME, Togo - An outbreak of bird flu has been confirmed in the West African nation of Togo for the first time since last year, the Health Ministry said Tuesday. A Togolese poultry farmer cares for his animals in the town of Baguida, June 2007. (TOGO) (BIRD FLU)

 

Togo says bird flu hits poultry farm

 

Tue Sep 9, 6:18 PM ET

 

LOME, Togo - An outbreak of bird flu has been confirmed in the West African nation of Togo for the first time since last year, the Health Ministry said Tuesday.

 

The virus was detected at a poultry farm housing more than 4,500 birds in the village of Agbata outside the capital, Lome, said a ministry statement read over state television. It was not known how many birds died, but more than 80 per cent of those infected by the flu were fatalities, the ministry said.

 

The statement did not say whether the birds were infected with the deadly H5N1 strain of the virus, which has scientists concerned because it has the potential to infect humans. At least 235 people have died of bird flu worldwide since 2003, according to the World Health Organization.

 

Most human cases have been linked to contact with infected birds, but health experts worry the virus could mutate into a form that passes easily among humans, sparking a pandemic that some say could kill millions of people and overload health care systems.

 

The Health Ministry banned the sale of all chicken and poultry products in the region around the farm.

 

AUG 2008

  

Fri Aug 01, 2:45 AM ET

Bird flu was discovered in a flock of 1,000 chickens in the southern province of Dong Thap on July 31, reported the Veterinary Agency. Image - Burying pigs in Thua Thien - Hue. (VIETNAM) (BIRD FLU)

 

Bird flu explodes in southern province Vietnam

 

Fri Aug 01, 2:45 AM ET

 

VietNamNet Bridge - Bird flu was discovered in a flock of 1,000 chickens in the southern province of Dong Thap on July 31, reported the Veterinary Agency.

 

With this new discovery, bird flu is currently in two provinces, Dong Thap and the central province of Nghe An.

 

Twelve provinces and cities in Vietnam have blue ear epidemic in pigs.

 

This disease is spreading its wings in the central province of Quang Nam.

 

Local authorities have decided to buy 20,000 doses of blue ear vaccine.

 

Another central province, Thua Thien-Hue, has said it will allocate VND270 million ($15,900) to prevent this disease.

 

So far, the province has culled more than 1,800 pigs.

 

(Source: NLD)

Fri Aug 01, 1:32 PM ET

The global threat of bird flu saved the Australian horse industry, experts say. (AUSTRALIA) (BIRD FLU) (GLOBAL PANDEMIC)

 

Bird flu saved horse industry: experts

 

Fri Aug 01, 1:32 PM ET

 

The global threat of bird flu saved the Australian horse industry, experts say.

 

In 2004, the CSIRO Australian Animal Health Laboratory developed a molecular diagnostic test for bird flu, at a time when equine influenza (EI) was not even on the radar.

 

Three years later, the same test was used in the effort to stop the spread of EI, with Agtrans Research saying it allowed authorities to determine the best ways to contain it.

 

"It's fortuitous that this diagnostic test could be applied to horse flu, as it's highly unlikely that a similar test could have been developed in a timely manner once the outbreak had been detected," Agtrans' Dr Peter Chudleigh said in a statement.

 

"The use of the test supported the decision to try for eventual eradication."

 

Dr Chudleigh said the main benefit from the diagnostic test was how quickly EI could be detected.

 

Australian Biosecurity Cooperative Research Centre chief executive Dr Stephen Prowse said the economic benefit of using the diagnostic test was more than $134 million.

 

"It took 125 days to eradicate equine influenza," he said.

 

But using the test enabled Australia to demonstrate freedom from the disease to the international community much earlier than would have otherwise been possible, he said.

 

"(And) at a much reduced expense to the industry, and freeing up horse movements," Dr Prowse said.

 

EI entered Australia through a Sydney quarantine centre, then spread through NSW and Queensland, shutting down the racing industry in those states for three months.

 

The breakout led to the cancellation of the 2007 Sydney Spring Carnival and the Queensland Summer Carnival, threatened the Melbourne Cup and disrupted breeding, exports and equestrian events.

 

The federal government is facing millions of dollars in compensation claims from the racing industry after a damning report blamed the quarantine authority for the devastating outbreak.

 

Australia was officially declared EI free on June 30, six months after the last detected case.

Sun Aug 3, 2:59 AM ET

Chickens are seen at a poultry house in Jakarta August 3, 2008. A 19-year-old Indonesian man died from bird flu last week, a health ministry official said on Sunday, bringing the total death toll from the virus in the Southeast Asian country to 112. REUTERS/Supri (INDONESIA) (BIRD FLU) (GLOBAL PANDEMIC)

 

Indonesian man dies of bird flu, official said Sunday, bringing the death toll to 112

 

Sun Aug 3, 2:59 AM ET

 

JAKARTA, Indonesia - An Indonesian factory worker died of bird flu, bringing the death toll in the country worst hit by the virus to 112, a top health official said Sunday.

 

The 19-year-old died last week in a hospital just west of the capital, Jakarta, Nyoman Kandun, the director general of communicable disease control at the Health Ministry, said by text message. He gave no additional information.

 

Indonesia has regularly recorded human deaths from bird flu since the virus began ravaging poultry stocks across Asia in 2003. Its toll of 112 accounts for nearly half the 240 recorded fatalities worldwide.

 

Bird flu remains hard for people to catch, but health experts worry that the virus could mutate into a form that passes easily between humans, possibly triggering a pandemic that could kill millions. So far most human cases have been linked to contact with infected birds.

 

Scientists have warned that Indonesia, which has millions of backyard chickens and poor medical facilities, is a potential hot spot for the start of a global pandemic.

Mon Aug 4, 7:12 AM ET

A few times each year, the world is reminded that a pandemic threat is immanent. In 2003, it was SARS. Today, it is a potential avian virus similar to the one that killed 30 million people after 1914. (BIRD FLU) (GLOBAL PANDEMIC)

 

A primer for pandemics

 

Mon Aug 4, 7:12 AM ET

 

A few times each year, the world is reminded that a pandemic threat is immanent. In 2003, it was SARS. Today, it is a potential avian virus similar to the one that killed 30 million people after 1914.

 

"Bird flu" has already shown that it can jump from fowl to humans, and now even to cats, which indicates that it might be the next global killer. But there are many other potential pandemics, and many are not even viruses. Bacteria, prions, parasites, and even environmental factors could suddenly change in a way that slays us. It is widely predicted that when this happens, the economic and human losses will exceed that of any previous war.

 

Indeed, it is humbling to remember that some of history's most deadly invasions were carried out by single-cell organisms, such as cholera, bubonic plague, and tuberculosis. Countries with the resources to do so are making resistance plans against pandemics &endash; limited strategies that would protect their own citizens. Most governments are hoping that early detection will make containment possible.

 

Containment depends heavily on vaccines, but vaccines are only part of the answer. While they are a good defense against many viruses, each vaccine is highly specific to the threat. Viruses are parasites to cells, and each virus attacks a particular type of cell. The virus is shaped so that it can drill into a particular feature of that cell and inject parts of itself inside, confusing the cell into making more viruses and destroying itself in the process. With their very specific forms, the most effective anti-viral vaccines must be designed for a narrow range of factors.

 

Sometimes the tailored nature of viruses works in our favor. For example, they usually find it difficult to jump between species, because they would have to change their structure. But if large numbers of a host, say, birds, encounter a great number of people, eventually the virus will find a way to prosper in a new type of cell.

 

Birds are the greatest concern today only because the spread is easy to see. But AIDS jumped from monkeys and several types of flu jumped from swine. Deadly mutations of any kind need to be identified urgently, so that an effective vaccine can be designed before the strain becomes comfortable in the human body. Unfortunately our present methods of detection are not sensitive enough.

 

This is even more worrying when you realize that scientists should also be monitoring bacteria, prions, and parasites. There are more bacteria than any other life form. Many live harmlessly in our bodies and perform useful functions. They evolve and adapt easily, which means that they learn to sidestep our drugs over time. Bacteria should be checked for two types of mutation: adaptation by a hostile form that enables it to become super-immune to drugs, or a deadly mutant strain that appears in one of the multitude of "safe" bacteria.

 

Prions are a relatively new discovery. They are made from proteins similar to those that the body uses during healthy operations, which means that they are able to fool the body's tools into making more prions. They have only recently been recognized as the cause of several infectious diseases, including mad cow disease and Creutzfeldt-Jakob Disease, which kill by crowding out healthy brain cells. Many nerve, respiratory and muscle diseases might also be caused by prions.

 

Finally, parasites, simple animals that infect us, are already classified as pandemics. Malaria afflicts 300 million people and is the world's biggest killer of children. Many parasites are worms: hookworm (800 million people infected), roundworm (1.5 billion), schistosomes (200 million), and the worm that causes Elephantiasis (150 million).

 

There are also antagonists that are currently ignored. Environmental chemicals and particulates might warrant their own categories. Or consider combinations of problems, such as these chemical infectors mixing with airborne pollens, and apparently pushing up incidences of asthma. New fungal infections are even scarier and might be harder to treat.

 

The bottom line is that we can't predict where the threat will emerge, so we need a distributed, intelligent detection system. In practical terms, how should it be built?

 

"Detectors" would have to be expert enough to know when an ordinary-looking symptom is actually an emergency. They would be located everywhere, with an emphasis on vulnerable regions. Initial warning signs of a pandemic are most likely to appear in the developing world, but detection nodes should be positioned in every country, with the least possible expense. This is not as difficult as it sounds. The key is to harness existing infrastructure.

 

Medical infrastructure exists everywhere, in some form. It also tends to be the least corrupt of institutions in regions where that is a problem. Medical centers and clinics would be expected to investigate the cause of ailments in a large number of their patients, even in cases where the symptoms seem common. A small amount of additional scientific expertise and lab equipment would need to be added to a public health system that serves ordinary needs.

 

Enhancing existing resources would be effective for two reasons. First, illness is more likely to be reported in a city hospital than at a specialist institute. Second, the investment would boost latent public health in that region.

 

For poor regions, investment in equipment and training would have to come from wealthier counterparts. Rich countries could justify the expense in terms of the savings that would result from early detection of a major threat. Tropical climates and urban slums are humanity's front line against pandemics, and they should be equipped properly.

 

Public health is an important asset for any nation. With so much at stake, it makes sense to place sentinels near every swamp, city, public market, and farmyard on earth.

 

By

H. T. Goranson is the Lead Scientist of Sirius-Beta Corp and was a Senior Scientist with the US Defense Advanced Research Projects Agency.

Wed Aug 6, 3:54 PM ET

State livestock and poultry officials say Arkansans can have complete confidence in the system that worked to quickly contain the bird flu outbreak back in June. (BIRD FLU) (AR)

 

State All Clear from Bird Flu - Arkansas

 

Wed Aug 6, 3:54 PM ET

 

State livestock and poultry officials say Arkansans can have complete confidence in the system that worked to quickly contain the bird flu outbreak back in June.

 

Thousands of chickens had to be destroyed at a farm near West Fork in Washington County after testing positive for the disease.

 

Thorough testing completed three weeks later gave the state the all clear.

 

"We did all of the surveillance work, tested birds in the area in a 6.2 mile area which is part of the protocol, and were completed and we had no more positives, it was just an isolated incident and hope we won't have anymore," says Jon Fitch, Director of the Arkansas Livestock & Poultry Commission.

 

Fitch says the state was well prepared thanks to training completed before the bird flu incident, but that there's nothing like learning from the real thing.

 

KARK 4 News

Wed Aug 6, 12:23 PM ET

MEDAN, Indonesia (AFP) - Three people have died and 13 have been admitted to hospital with symptoms of bird flu in Indonesia, a nurse treating the patients said Wednesday. (BIRD FLU) (INDONESIA)

 

Three dead in feared bird flu outbreak in Indonesia: officials

 

Wed Aug 6, 12:23 PM ET

 

MEDAN, Indonesia (AFP) - Three people have died and 13 have been admitted to hospital with symptoms of bird flu in Indonesia, a nurse treating the patients said Wednesday.

 

Officials and residents in Asahan district of North Sumatra province said villagers began showing symptoms of avian flu after a large number of chickens died suddenly last week.

 

The nurse at Asahan district's Kisaran hospital said three people had died after suffering bird flu-like symptoms in Air Batu village.

 

"According to residents there, a number of chickens died suddenly last week followed by several pigeons. Days later, three people died with the same ailments," the nurse, Mariana, told AFP.

 

Another 13 people had been admitted to the hospital with "high temperatures and respiratory problems," she said.

 

Two of these -- a baby boy and a seven-year-old girl -- were transferred early Wednesday to a bird flu isolation unit at Adam Malik hospital in the provincial capital of Medan, officials said.

 

Adam Malik hospital spokesman Sinar Ginting confirmed that blood samples from the two children were sent Wednesday to a health ministry laboratory in Jakarta for analysis.

 

"We are now waiting for the result," he said.

 

The father of the baby boy, Slamet Riadi, said a lot of poultry had died in the village a week ago. His baby developed a high fever and respiratory problems shortly afterward.

 

A spokeswoman for the health ministry could not be reached for comment.

 

The ministry, which has stopped giving regular bird flu updates, announced earlier this week that the human toll from avian influenza in Indonesia had risen to 112 with the recent death of a 19-year-old man.

 

The man was from a town adjoining the capital Jakarta on Java island.

 

Indonesia is the country worst-hit by the deadly H5N1 strain of bird flu, which can be passed from bird to human.

 

Experts fear it could mutate into a form easily transmissible between humans and kill millions in a global pandemic.

Thu, Aug 7 12:59 PM

A rooster perches on a cage at a traditional market in Medan, North Sumatra, Indonesia, Thursday, Aug. 7, 2008. Thirteen people hospitalized with high fevers and respiratory problems are being treated as suspected bird flu patients after dozens of chickens died of the disease in their tiny Indonesian village, a health official said Thursday. (AP Photo/Binsar Bakkara) (BIRD FLU) (INDONESIA)

 

Indonesia testing 13 for bird flu in Sumatra village

 

Thu, Aug 7 12:59 PM

 

JAKARTA (Reuters) - Thirteen people from a village in North Sumatra are due to be tested for bird flu after falling sick, Indonesian health.

 

The 13, from Air Batu village, were hospitalised this week after suffering fever, but their conditions had improved on Thursday and they might not be suffering from the disease, a health official said.

 

A bird flu surveillance team from Indonesia's health ministry has been sent to the area.

 

"Although they found dead chickens in the area, the symptoms are not like bird flu," said Erna Tresnaningsih, the health ministry's director of animal-borne disease control.

 

A seven-year-old girl and an eight-month-old child were being treated in Adam Malik hospital in North Sumatra's capital Medan with Tamiflu, the medication most often used to treat bird flu, said hospital spokesman Sinar Ginting.

 

A spokeswoman for the World Health Organisation said she was not authorised to comment on the case.

 

The country's largest known cluster of bird flu cases in humans occurred in May 2006 in the Karo district of North Sumatra province, where as many as 7 people in an extended family died.

 

The World Health Organisation said at the time that limited human-to-human transmission could not be ruled out but that the virus samples from the scene did not show any significant genetic mutations.

 

Ginting was quoted by media as saying on Wednesday that not all the patients were believed to have had contact with fowl, which is the most common way of contracting the H5N1 bird flu virus, after some chickens in the area had died suddenly and were found to have been infected.

 

Suspected cluster cases can raise concerns about rare human-to-human transmission or that the virus might have mutated into a form that can pass easily among people, triggering a pandemic.

 

Bird flu remains mainly an animal disease but experts fear the H5N1 virus might mutate into a pandemic strain that would sweep the globe, possibly killing millions and hobbling economies.

 

Health experts say monitoring of the virus across Indonesia's thousands of islands to detect any genetic changes is vital, but there has been some confusion over the government's stance on reporting cases.

 

Indonesian Health Minister Siti Fadillah Supari, who has clashed with the international community over virus sharing, said in early June her ministry would only report cases every six months, although the ministry has reported three deaths since.

 

The virus is known to have infected 385 people in 15 countries, killing 243 of them since late 2003, according to the WHO's June 19 tally.

 

Indonesia reported on Sunday that a 19-year-old man died from bird flu last week, bringing the total death toll in the Southeast Asian country to 111, the highest of any nation.

Sat, Aug 9 5:00 AM

Geoffrey Buchanan was fined by Bury St Edmunds magistrates. (UK) (BIRD FLU)

 

Court fines bird flu case Suffolk farmer

 

Sat, Aug 9 5:00 AM

 

A Suffolk farmer whose business was at the centre of a bird flu outbreak has been fined £4,000 for breaching regulations during the crisis.

 

Geoffrey Buchanan, 38, a director of Gressingham Foods, based in Debach, admitted eight offences relating to the storage and movement of carcasses.

 

Magistrates in Bury St Edmunds, Suffolk, sat late into the evening to sentence Buchanan

 

He was also ordered to pay £3,510 costs and a £15 victim surcharge.

 

Suffolk County Council's trading standards department, which brought the prosecution, said the charges followed, but were not directly linked to, the outbreak of the deadly H5N1 strain of the disease in Redgrave, Suffolk in November last year.

 

'Significant concerns'

 

After the case, Mike Collins, who investigated the case, said he was happy with the outcome.

 

"The legislation is there for a reason - to stop the spread of the disease," he said.

 

"During an avian influenza outbreak, when there are significant concerns about the about the disease and the implications for other farmers, breaking the rules is a very serious offence.

 

"During an outbreak, even greater care should have been taken and clearly it wasn't by Mr Buchanan."

 

Buchanan, in a statement read outside court, said: "We very much regret our involvement in this offence and accept the sentence imposed by the court."

 

He added: "We wish to make it abundantly clear that these offences are not linked with the avian influenza outbreak in 2007."

 

The bird flu virus was discovered at Redgrave Park Farm, which is owned by Gressingham Foods, near Diss, in November 2007, where thousands of birds were slaughtered.

Sat, Aug 9 7:36 AM

Thirteen people in Indonesia suspected of having bird flu have tested negative for the feared disease, the country's health ministry said Saturday. (INDONESIA) (BIRD FLU)

 

Indonesian villagers test negative for bird flu: health ministry

 

Sat, Aug 9 7:36 AM

 

Thirteen people in Indonesia suspected of having bird flu have tested negative for the feared disease, the country's health ministry said Saturday.

 

Experts from the World Health Organisation (WHO) arrived Friday in the affected village in North Sumatra to help investigate a possible outbreak after three people died and the 13 were admitted to hospital.

 

"All specimens collected from suspect cases have given negative results. They are all recovered," I Nyoman Kandun, director general of the ministry's communicable diseases department said on a text message.

 

Officials and residents in Asahan district in North Sumatra province said villagers began showing symptoms of avian flu after a large number of chickens died suddenly last week in Air Batu village.

 

The local husbandry office took preventive action this week by slaughtering and burning some 400 chickens and ducks.

 

The ministry, which has stopped giving regular bird flu updates, announced earlier this week that the human toll from avian influenza in Indonesia had risen to 112 following the recent death of a 19-year-old man.

 

The deadly H5N1 strain of bird flu has killed more than 240 people worldwide since late 2003.

 

The virus typically spreads from bird to human through direct contact, but experts fear it could mutate into a form easily transmissible between humans, with the potential to kill millions in a pandemic.

 

Sun, Aug 10 12:03 PM

During the bird flu scare, duck sales soared while chicken suffered. Among the fast-changing trends of international cuisine, Peking Duck is a rare enduring classic, with a history stretching back 1,600 years. (BIRD FLU)

 

Peking Duck is a rare enduring classic, with a history stretching back 1,600 years.

 

Sun, Aug 10 12:03 PM

 

Among the fast-changing trends of international cuisine, Peking Duck is a rare enduring classic, with a history stretching back 1,600 years.

 

Indeed, demand for the dish is so high that the most popular venues are not just single restaurants but chains of restaurants. Quanjude, for example, is listed on the stock exchange.

 

Quanjude (the name means "a complete gathering of virtues") is currently top of the pops for Peking Duck but is no longer the only famous chain serving it. Da Dong, named after its chef and founder, is popular among expats and has become famous for its light and healthy twist on Shandong and Beijing foods.

 

The grand-daddy of them all, Bianyifang has just opened its latest branch by the 4th Ring Road in southwest Beijing, with both a modern and traditional dcor. It even has a Peking Duck museum to illustrate the history and techniques involved in the making of the legendary dish.

 

Bianyifang was established in 1416, while Quanjude would be founded in 1864. It is also making constant innovations to its duck dishes, including a roast duck de-greased with vegetable juice.

 

Other popular roast duck restaurants include Ya Wang (King Roast Duck) and Li Qun, a courtyard restaurant. For a more Western-style Peking Duck, many people visit Made in China, which offers a wide range of Chinese foods with a modern twist, with wines to match them.

 

But if Peking Duck were an Olympic event, it would be Quanjude that has a clear lead. Its founder, Yang Quanren, made a living 140 years ago by selling ducks and chickens at a meat market, before moving on to having his own shop. Within a year, Yang had hired several assistants and changed the old closed-oven roast method to new open-oven roasting, so as to simplify and expand production. Quanjude is now so famous it has been featured in several Chinese films and TV dramas.

 

Today, it issues a certificate to every customer who orders Peking Duck. The number of ducks it has roasted now exceeds 100 million, which explains why Quanjude has become a popular choice for investors since being publicly listed.

 

At all major roast duck restaurants, the duck is roasted upon order and sliced right next to you. It is served with slices of spring onion, cucumber, sweet brown sauce and flour pancakes to wrap the duck and side dishes into a roll. The roast duck looks temptingly golden brown and the fragrance is or should be irresistible.

 

For the more adventurous diner, restaurants often have dishes prepared with duck parts and giblets, such as quick-fried duck heart with coriander, salty poached duck liver and duck feet with mustard. The bones can also be made into a milky white tasty soup.

 

The success of any dish depends primarily on its great taste, and competitors are constantly experimenting to improve the flavor. Da Dong's super-lean Peking Duck prolongs the 45-minute roasting process to an hour and 10 minutes, further reducing the grease and improving the flavor. Quanjude has introduced new flavors such as mustard to accompany duck dishes, while Bianyifang adds lettuce, fresh mint, turnip and leafy sprouts. Over the years, the dish has become less oily but just as tasty.

 

Last year, Quanjude got a public roasting over its plan to use more electric ovens, citing them as a cleaner and more practical way of cooking. An Internet survey showed 77 percent of netizens were against the move, because fruitwood used in roast ovens had become part of the attraction of Peking Duck over the years. People worried that the famous old dish would become more like simple fried chicken. The age-old image of a master chef roasting a duck at a 6-foot-high drum-shaped oven heated with fruitwood proved resilient to the new notion of replacing it with a piece of metal. Quanjude eventually backed down.

 

Taste is not the only reason for Peking Duck's unique status, though. The Chinese believe that other poultry is hot in nature and therefore brings excessive heat to the body. Duck, however, is considered moderate, even slightly cold, because it comes from water and it is believed to be good for the lungs and other parts of the respiratory system. During the bird flu scare, duck sales soared while chicken suffered. Moreover, roasting duck neutralizes its innate coldness and is thought to make it a really balanced food.

 

So where is Peking Duck headed? Chain founder Da Dong believes it must become "a living piece of history", combining elements of old and new. "Today's science and technology can guarantee the efficient filtering of smoke and oil, ensuring that the fruitwood heating system meets health and environmental requirements," he says.

 

Quanjude and Bianyifang are both applying for their roasting processes to be declared worthy of cultural heritage status and thus worth preserving. The two restaurants have also set up museums showcasing how Peking Duck has stood the test of time and remained a favorite food for the Chinese.

 

Meanwhile, restaurants like Da Dong keep in touch with master chefs from other countries, so helping to keep them in the forefront of world cuisines.

 

"But most importantly, we've followed the traditions of Chinese cuisine," says Dong. "Although we are modern and fashionable, the core of our cuisine is Chinese."

 

 

By Ye Jun (China Daily)

 

Tue Aug 12, 8:12 AM ET

A poultry market in Lagos in 2007. The UN food agency has said that a strain of highly pathogenic bird flu previously not recorded in sub-Saharan Africa has been detected in Nigeria. (AFP/File/Pius Utomi Ekpei) (BIRD FLU) (NIGERIA) (BIRD FLU STRAINS)

 

New bird flu strain detected in Nigeria: FAO

 

Tue Aug 12, 8:12 AM ET

 

ROME (AFP) - A strain of highly pathogenic bird flu previously not recorded in sub-Saharan Africa has been detected in Nigeria, the UN food agency said Tuesday.

 

Laboratory results from Nigeria and a Food and Agriculture reference laboratory in Italy show that the newly discovered virus strain is genetically different from the strains that circulated in Nigeria in 2006 and 2007, the Rome-based agency said in a statement.

 

"The detection of a new avian influenza virus strain in Africa raises serious concerns as it remains unknown how this strain has been introduced to the continent," warned Scott Newman of the FAO's Animal Health Service.

 

The new strain is similar to ones previously identified in Italy, Afghanistan and Iran last year, the FAO said.

 

"It seems to be unlikely that wild birds have carried the strain to Africa, since this year's southerly migration into Africa has not really started yet," Newman said, suggesting "other channels for virus introduction (including) international trade or illegal and unreported movement of poultry.

 

He warned that this increased the risk of avian influenza spreading to other countries in western Africa.

 

Since the avian influenza epidemic caused by the H5N1 strain started five years ago in Asia, the disease has affected more than 60 countries, most of which have succeeded to eliminate the virus from poultry, the FAO said.

 

In Nigeria, the virus was first confirmed in February 2006 and infected poultry in 25 states before being contained, but the west African economic powerhouse has recently reported two new highly pathogenic bird flu outbreaks in the northern states of Katsina and Kano.

Tue Aug 12, 8:02 PM ET

WASHINGTON (Reuters) - Countries around the world may be preparing for a possible H5N1 bird flu pandemic, but another strain called H9N2 also poses a threat to humanity, researchers reported on Tuesday. (RESEARCH) (BIRD FLU)

 

New bird flu threat could be H9N2, researchers say

 

Tue Aug 12, 8:02 PM ET

 

WASHINGTON (Reuters) - Countries around the world may be preparing for a possible H5N1 bird flu pandemic, but another strain called H9N2 also poses a threat to humanity, researchers reported on Tuesday.

 

Tests on the H9N2 strain of the virus show it is capable of infecting and spreading with very few changes, a team from the University of Maryland, St. Jude's Children's Research Hospital in Memphis, and elsewhere reported.

 

"Our results suggest that the establishment and prevalence of H9N2 viruses in poultry pose a significant threat for humans," the researchers wrote in the Public Library of Science journal PLoS ONE.

 

Most influenza experts agree that a pandemic -- a deadly global epidemic -- of some kind of flu is inevitable.

 

No one can predict what kind but the chief suspect is the H5N1 bird flu virus, which has infected 385 people and killed 243 of them since 2003. It is entrenched in birds now in some areas and has killed or forced the slaughter of 300 million.

 

Just a few mutations could turn it into a virus that people catch and transmit easily. But flu experts caution H5N1 is not the only virus with this potential.

 

H9N2, a virus seen mostly in birds, has infected at least four children in Hong Kong, causing mild illness, and is found in birds, pigs and other animals in Europe and Asia.

 

Maryland's Daniel Perez and colleagues tinkered with the virus and tested it in ferrets, animals whose biology is very close to humans when it comes to flu.

 

A single mutation made H9N2 more virulent and pathogenic, and also helped it transmit more easily from one ferret to another, they reported in their study, available on the Internet at http://dx.plos.org/10.1371/journal.pone.0002923.

 

They also mixed H9N2 with an H3N2 virus, a type of influenza virus that causes seasonal flu in people. Scientists believe that if a human or animal is infected with two strains of flu at the same time, this "reassortment" can happen in nature.

 

The reassorted virus was easier for the ferrets to catch and transmit.

 

One reassuring finding -- neither of the lab-engineered viruses could be transmitted in the air, via aerosol. This might make them somewhat less transmissible, although people pick up flu from surfaces touched by an infected person.

 

"Although no aerosol transmission was observed, the virus replicated in multiple respiratory tissues and induced clinical signs similar to those observed with the human H3N2 virus," the researchers wrote.

 

There are hundreds of strains of avian influenza viruses, but only fou , H5N1, H7N3, H7N7, and H9N2, are known to have caused human infections, according to the World Health Organization.

 

(Reporting by Maggie Fox, editing by Will Dunham)

Wed Aug 13, 1:33 PM ET

ABUJA (Reuters) - Infected migratory birds from Europe or Central Asia were probably to blame for spreading a new strain of H5N1 bird flu to Africa, Nigeria's chief bird flu expert said on Tuesday. (BIRD FLU) (NIGERIA) (BIRD FLU STRAINS)

 

Wild birds maybe caused new flu strain: Nigeria

 

Wed Aug 13, 1:33 PM ET

 

ABUJA (Reuters) - Infected migratory birds from Europe or Central Asia were probably to blame for spreading a new strain of H5N1 bird flu to Africa, Nigeria's chief bird flu expert said on Tuesday.

 

The United Nations Food and Agriculture Organization reported on Monday that the strain of avian influenza recently found in Nigeria was genetically different from the strains in previous African outbreaks.

 

Mohammed Saidu, head of Nigeria's bird flu control program, said the H5N1 strain was discovered last month in a duck at a poultry market in northeast Gombe state.

 

"Since that location is among the 24 wetlands we have in Nigeria and along the two migratory routes, we suspect that the strain could have come from the migratory birds," Saidu said.

 

A senior FAO official on Monday expressed doubts that wild birds carried the strain to Africa since this year's southerly migration has yet to begin.

 

Scott Newman, International Wildlife Coordinator of FAO's Animal Health Service, said the virus may have instead reached the continent via international trade.

 

In late July, Africa's most populous country discovered its first cases of H5N1 bird flu virus in almost 10 months. The virus, which can spread to humans, was found in poultry markets in the northern cities of Kano and Katsina.

 

Avian influenza is common, but the H5N1 strain is particularly worrying both to poultry producers and doctors.

 

It rarely infects people but has killed 243 out of 385 known to have been infected since 2003, according to the World Health Organization. It has killed or forced the slaughter of 300 million birds.

 

(Writing by Randy Fabi; Editing by Tume Ahemba)

Wed Aug 13, 6:31 PM ET

A worker selects chickens before sending them to the market from a poultry house in Jakarta August 3, 2008. REUTERS/Supri (INDONESIA) (BIRD FLU)

 

More than 80 pct of Indonesia bird flu cases die

 

Wed Aug 13, 6:31 PM ET

 

WASHINGTON (Reuters) - Late diagnosis and treatment means that more than 80 percent of people infected with H5N1 avian influenza in Indonesia have died, researchers reported on Wednesday.

 

An analysis of outbreaks in Indonesia, the country hardest hit by bird flu, affirms that quick treatment with antiviral drugs can save lives. But local health care workers are not properly trained in diagnosing bird flu and often do not have the needed drugs to treat it.

 

Indonesia has had one-third of the world's known cases of human infection with H5N1 avian influenza. It rarely infects people but globally has killed 243 out of 385 sickened since 2003. In Indonesia, 135 people have been infected and 110 have died, according to the World Health Organization.

 

Dr. Toni Wandra of the Ministry of Health in Jakarta and colleagues analyzed the known cases as of February and found it took on average six days for patients to be admitted to a hospital.

 

By the time they were admitted, 99 percent had a fever, 88 percent were coughing and 84 percent had breathing problems, they reported in the Lancet medical journal.

 

But for the first two days they were ill, most patients had hard-to-identify symptoms, only 31 had both fever and cough, and nine had fever and breathing problems.

 

On average it took seven days to get oseltamivir, Roche AG and Gilead Sciences Inc's Tamiflu.

 

More than a third of patients who got Tamiflu within six days survived, compared to 19 percent treated at seven days or later survived.

 

This confirms other research that shows treatment with flu drugs such as Tamiflu needs to start right away to be effective, they said.

 

"There is a clear need to identify definite causes for high-case fatality," Wandra's team wrote.

 

"Poultry surveillance is being stepped up, and active human case finding by local health centers and village officials is being instituted in areas of poultry deaths."

 

Workers need to be trained in getting information about whether patients with flu-like symptoms were around sick poultry, they added.

 

"Finally, all health-care workers should be trained in case management of early H5N1 influenza, and should be equipped with oseltamivir to enable timely administration."

 

H5N1 currently infects mostly birds and has killed or forced the destruction of 300 million in Asia, Europe, the Middle East and Africa.

 

It rarely infects humans and almost all cases have been infected by sick birds. Doctors fear it could change into a form that easily infects people, in which case it could sweep the world, killing millions of people in months.

 

Tamiflu and GlaxoSmithKline's and Biota's Relenza can treat the infection, but are in short supply, and a vaccine would take months or years to manufacture and deliver.

 

Thu Aug 14, 2:45 PM ET

Officials from the Ministry of Health and Social Services, marine experts, and representatives of the Police and the Namibian Defence Force are in Walvis Bay for a two-day workshop on avian influenza, commonly referred to as bird flu. (BIRD FLU)

 

Namibia: Health Experts, Security Personnel Meet Over Bird Flu

 

Thu Aug 14, 2:45 PM ET

 

Officials from the Ministry of Health and Social Services, marine experts, and representatives of the Police and the Namibian Defence Force are in Walvis Bay for a two-day workshop on avian influenza, commonly referred to as bird flu.

 

The workshop is aimed at formulating a Rapid Response Team at local level to complement the country's efforts as part of SADC countries' efforts to control the spread of the disease. The workshop follows an earlier visit by representatives of the FAO to the coastal towns to assess the implementation of avian influenza response.

 

At SADC level, the Centre for Disease Control (CDC) in South Africa organised similar workshops where training and sensitisation on bird flu was provided. The training was aimed at passing on knowledge to the various countries' representatives, who would in turn pass over the knowledge to relevant stakeholders in their own countries.

 

Avian influenza is an infection caused by avian (bird) influenza viruses. These influenza viruses occur naturally among birds. Wild birds worldwide are reported to carry the viruses in their intestines, but usually do not get sick from them. However, avian influenza is very contagious among birds and can infect domesticated birds, including chickens, ducks, and turkeys, often killing them.

 

Infected birds shed influenza virus in their saliva, nasal secretions, and faeces. Susceptible birds become infected when they have contact with contaminated secretions or excretions or with surfaces that are contaminated with secretions or excretions from infected birds. Domesticated birds may become infected with avian influenza virus through direct contact with infected waterfowl or other infected poultry, or through contact with surfaces (such as dirt or cages) or materials (such as water or feed) that have been contaminated with the virus.

 

Migratory birds making their way into other countries beyond their origins have been reported as one of the major factors fuelling the spread of bird flu to those countries. Due to the large presence of migratory birds often found along the Namibian shores and coastline, the Ministry of Health deemed it necessary to convene the workshop as a direct response to earlier regional efforts to prevent a catastrophe in the event of another outbreak of the disease.

 

Infection with avian influenza viruses in domestic poultry causes two main forms of disease that are distinguished by low and high extremes of virulence. The "low pathogenic" form may go undetected and usually causes only mild symptoms (such as ruffled feathers and a drop in egg production).

 

However, the highly pathogenic form, H5N1 virus, spreads more rapidly through flocks of poultry. This form may cause diseases that affect multiple internal organs and has a mortality rate that can reach 90-100 percent often within 48 hours.

 

The State veterinarian at Walvis Bay, Dr Elizabeth Homateni-Kamberuka, who is facilitating the workshop, said the workshop became vital in order to form a Rapid Response Team that would be deployed in the event of an outbreak of bird flu.

 

"This workshop is important for the region to be prepared and respond as rapidly as possible in the case of an outbreak, as these people will be deployed in the field to deal with a confirmed or suspected outbreak of Avian influenza in humans or birds," she said.

 

Although the H5N1 virus does not usually infect people, infections with these viruses have been reported in humans. Most of these cases have resulted from people having direct or close contact with H5N1-infected poultry or H5N1-contaminated surfaces.

 

Of the human cases associated with H5N1 outbreaks in poultry and wild birds, more than half of the people reported to be infected with the virus have died. Most cases have occurred in previously healthy children and young adults and have resulted from direct or close contact with H5N1-infected poultry or H5N1-contaminated surfaces. In general, H5N1 remains a very rare disease in people. The H5N1 virus does not infect humans easily, and if a person is infected, it is very difficult for the virus to spread to another person.

 

While there has been some human-to-human spread of H5N1, it has been limited, inefficient and unsustained. Nonetheless, because all influenza viruses have the ability to change, scientists are concerned that H5N1 virus one day could be able to infect humans and spread easily from one person to another.

 

Charles Tjatindi

Walvis Bay

Thu Aug 14, 5:15 PM ET

A file photo of a bird vendor on his way to a Buddhist pagoda in Vientiane. Laos. A new Veterinary Law passed on 25 July is good news in the fight against avian influenza (AI - bird flu), given that Laos is surrounded by neighbours that have suffered severe AI outbreaks. (BIRD FLU)

 

LAOS: New veterinary law targets bird flu

 

Thu Aug 14, 5:15 PM ET

 

VIENTIANE, A new Veterinary Law passed on 25 July is good news in the fight against avian influenza (AI - bird flu), given that Laos is surrounded by neighbours that have suffered severe AI outbreaks.

 

"This is a significant milestone in infectious disease preparedness for this country," Subhash Morzaria, the AI programme team leader of the UN Food and Agriculture Organization (FAO) in Laos, told IRIN. "It is an indication that the government recognises the significance of animal - and public - health and the importance of ensuring bio-food security," Morzaria said.

 

The Veterinary Law 2008 establishes a regulatory framework to strengthen veterinary services, contains provisions for greater transparency in reporting AI and other emerging diseases, and sets out disease control measures, including animal and by-product movements, bio-security and hygiene standards.

 

Because poultry is one of the cheapest sources of protein, Morzaria explained, failure to protect it could worsen food security and poverty. Strong measures to safeguard the health of animals against infectious diseases such as AI are therefore of the utmost importance, he said.

 

Last year, two people died in Laos from highly pathogenic avian influenza (HPAI), and another outbreak earlier this year resulted in the culling of 5,000 poultry in six northern villages of Luang Nam Thaa Province, according to the authorities.

 

However, mountainous Laos, with its low population density and scattered poultry farming, has been spared the severity of AI outbreaks in Vietnam and China, according to Kristina Osbjer, operations officer with the FAO AI Programme. Laos thus has some breathing space to develop disease preparedness strategies, she said, but the country lacks basic infrastructure, and its porous borders make it a likely victim of further AI outbreaks.

 

FAO working with government on capacity building

 

"Short- and long-term capacity are major issues in Laos," explained Osbjer. "We are therefore working with the government to provide capacity building at grassroots level so they can identify the disease and respond faster to nip it in the bud before it becomes entrenched."

 

The programme includes training veterinary staff, animal health workers and village veterinary workers in surveillance techniques; improved detection; and systematic recording and reporting of suspected AI cases.

 

FAO is also leading an active surveillance project on domestic fowl with the Department of Livestock and Fisheries, focusing on the most at-risk sites. To complement the enhanced surveillance and identification capacities, FAO is expanding the laboratory capacity of the National Animal Health Centre to conduct improved serology and virus isolation on an increased number of samples, said Osbjer.

 

Awareness raising

 

Reinforcing all this work is the communications programme led by the UN Children's Fund (UNICEF) which is ensuring that prevention, recognition and containment information reaches all strata of society.

 

"Getting out the message about the threat posed by AI has been absolutely central to the whole campaign," said UNICEF head of communications in Laos Simon Ingram. "Thanks to some generous funding that we received from the government of Japan in 2006, UNICEF has supported a massive public information campaign delivering key prevention messages to millions of families, using everything from radio and TV spots to touring puppet troupes and networks of village leaders."

 

While considerable achievements have been made to prepare Laos for future AI outbreaks, Osbjer said the new Veterinary Law alone would not be enough. "We must stress the need for long-term capacity in the animal and public health sector - not just to deal with avian influenza but all infectious diseases. And for that, the government must educate more staff."

Fri Aug 15, 6:56 AM ET

A chicken among 2,700 birds about to be slaughtered by workers from the Health and Environmental Hygiene Department is seen in a market after it was declared an infected area in Hong Kong June 7, 2008. (Bobby Yip/Reuters) (BIRD FLU) (HUMAN BIRD FLU)

 

H9N2 bird flu threat understated in humans

 

Fri Aug 15, 6:56 AM ET

 

HONG KONG (Reuters) - The H9N2 bird flu strain, identified as a possible pandemic threat, could be infecting more humans than commonly thought but its mild symptoms mean it often goes undetected, a leading Hong Kong bird flu expert said.

 

"It's quite possible, H9N2 is infecting humans quite a lot, much more than we appreciate merely because it is beyond the radar," Malik Peiris, a Hong Kong-based microbiologist, told Reuters.

 

"In humans, it is very mild, so most of the time it's probably not even recognized or biologically tested," said Peiris, who has co-authored several papers on the strain in recent years.

 

So far, only a handful of human H9N2 cases have been documented worldwide, including four children in Hong Kong in 2003 who suffered from mild fevers and coughs, as well as a batch in China's Guangdong province, where people often live in close proximity to poultry, Peiris said.

 

The Hong Kong cases were only picked up by chance given the city's rigorous influenza testing regime, Peiris said.

 

"It's quite a silent virus, it's not highly pathogenic and sometimes it causes some morbidity in poultry but by and large it is just there and it's unnoticed," Peiris said of the H9N2 strain.

 

The strain occurs mostly in birds, although it has also affected pigs and other animals in Europe and Asia.

 

Most influenza experts agree that a pandemic, a deadly global epidemic, of some kind of flu is inevitable.

 

No one can predict what kind but the chief suspect is the H5N1 bird flu virus, which has infected 385 people and killed 243 of them since 2003.

 

However, flu experts at the University of Maryland, St. Jude's Children's Research hospital in Memphis and elsewhere recently wrote in the Public Library of Science journal PLoS ONE that the H9N2 strain posed a "significant threat for humans."

 

They found that just a few mutations could turn it into a virus that people catch and transmit easily.

 

Peiris said that while the H9N2 strain might be more transmissible, its effects would be far less devastating than a possible H5N1 pandemic.

 

"There are other viruses out there besides H5N1 that could be the next pandemic," Peiris said. "But I suspect (H9N2) will not be so severe in its outcome."

 

Peiris pointed out that the last three major pandemics vastly differed in their severity, with the 1918 Spanish flu pandemic killing an estimated 50 million people worldwide, whereas the "Hong Kong" flu in 1968 killed around one million.

 

There are hundreds of strains of avian influenza virus but only four: H5N1, H7N3, H7N7, and H9N2, are known to have caused human infections, according to the World Health Organization.

 

(Reporting by James Pomfret; Editing by Paul Tait)

 

Sat Aug 16, 2:45 AM ET

VietNamNet Bridge - The Food and Agriculture Organisation of the United Nations (FAO) recommended yesterday that Viet Nam consider moving from a fully publicly-funded bird flu mass-vaccination campaign, to a public-private funded one to ease the burden on the State as donations are on the decline, according to FAO's senior avian influenza technical consultant Dr Tony Forman. (BIRD FLU)

 

FAO recommends cost-sharing to deliver bird flu vaccinations

 

Sat Aug 16, 2:45 AM ET

 

"We have to recognise that this disease is going to continue for a long time. One thing that the Government and FAO are concerned about is that the strategies we have for controlling bird flu be sustainable," said the animal health expert on the sidelines of a two-day meeting to review the Strategy for Control and Prevention of Highly Pathogenic Avian Influenza in the Agriculture Sector in Ha Noi.

 

Cost-sharing was one of strategies being discussed in a bid to sustain control as donations drop, he said.

 

Viet Nam has spent around US$20 million a year on bird flu vaccinations, including about 500 million doses of vaccines since the disease first broke out in the country in 2003; this fund comes mostly from donors.

 

Free Tamiflu

 

The Government of Japan will provide Viet Nam with Tamiflu, enough to help about 74,000 people.

The donation ceremony was held yesterday in Ha Noi between the Japanese Embassy and the Ministry of Health.

 

According to Forman, the level of funds from major donors is still good, the US Agency for International Development being the largest one, but support from other donors have already started dropping off.

 

He explained the problem was that a lot of international support came from various governments' emergency funding for Viet Nam. But the country had escaped being one of the bird flu centres in the world, said Agriculture and Rural Development Deputy Minister Bui Ba Bong.

 

Forman said Viet Nam was without question, doing a much better job in controlling the disease than other countries in the world thanks to the Government's strong commitment, but it was very expensive to undertake control in this way.

 

Le Thanh Binh, a farmer in Vinh Phuc Province, said if she had to pay for vaccinations, she would only vaccinate her family's small chicken flock in case there was an outbreak in her area.

 

Some believe the new mechanism might discourage farmers from vaccinating their birds, because ironically, the Government's success in controlling the disease had led to a drop in their awareness of the dangers.

 

The FAO agreed it was a risk and a challenge to encourage cost sharing. Therefore, they recommended implementing the mechanism on a trial basis to see what level of support from the Government would be appropriate, said Forman.

 

"That is why the Government will continue one mass vaccination each year [instead of the current two] in October and November, to ensure that the birds are covered over this high risk period of Tet (Lunar New Year), in case the funding fails."

 

According to the FAO representative in Viet Nam, Andrew Speedy, public-private cost sharing will not only enable the Government at the central, provincial and district levels to have some budgetary reserves for supporting other key disease prevention and control programmes, but is also likely to bring about a sense of ownership and stronger participation in the vaccination policy by all those involved in the poultry business.

 

(Source: VNS)

Sat Aug 16, 5:45 AM ET

The Ministry of Agriculture and Rural Development (MARD) has asked localities, agencies and farmers to strictly observe bird flu inoculation regulations to ensure that all poultry is vaccinated. (VIETNAM) (BIRD FLU)

 

Ministry requests acceleration of bird flu vaccination - Vietnam

 

Sat Aug 16, 5:45 AM ET

 

The Ministry of Agriculture and Rural Development (MARD) has asked localities, agencies and farmers to strictly observe bird flu inoculation regulations to ensure that all poultry is vaccinated.

 

Deputy Minister of Agriculture and Rural Development Bui Ba Bong told a recent meeting that vaccination against H5N1 virus is the most efficient measure in preventing bird flu, as more than 90 percent of affected poultry are not vaccinated or inadequately vaccinated.

 

The Prime Minister in June decided not to provide financial assistance for those bird flu-hit farmers who did not observe regulations on vaccination against the deadly virus.

 

In an effort to prevent the spread of bird flu, the MARD also requested veterinary agencies at localities to closely monitor and grant quarantine certificates for the transportation of poultry.

 

Vietnam is recognised as one of the world's most successful nations in fighting bird flu and is no longer an epidemic centre in Southeast Asia .

 

With efforts made by localities and agencies, bird flu has been no longer widespread and total losses caused by the deadly virus has decreased, even though the epidemic has still recurred annually since it appeared in the country for the first time in 2003.

 

So far this year, bird flu outbreaks have only occurred on a small scale among flocks of unvaccinated poultry.

Sat Aug 16, 3:26 PM ET

British scientists have developed portable technology which can detect bid flu in two hours (BIRD FLU)

 

Scientists develop new machine which can detect bird flu outbreaks in just TWO hours

 

Sat Aug 16, 3:26 PM ET

 

British scientists are developing revolutionary technology which can detect outbreaks of bird flu in just two hours, paving the way for a swift end to a potential pandemic.

 

It currently takes up to a week to identify different types of bird flu, including the potentially fatal H5N1 strain.

 

But scientists at Nottingham Trent University say they are now helping to develop a portable machine - the size of a briefcase - to be used at potential sites of  an outbreak.

 

They are also trying to build a model that can carry out the same task in hospitals in an effort to speed up the time it takes to diagnose suspected human cases.

 

The technology works by recognising molecules from a swab of human saliva or animal tissue, before identifying if it is infected with bird flu and if so which strain is present.

 

The university says the technology will mean officials can set up exclusion zones and cull infected birds much faster.

 

Dr Alan McNally, a former avian flu researcher for the Government who is working on the project, said the process will be fully automated and could be used by someone who is unskilled in using the technology.

 

'At present tests have to be sent to a lab where you need fully trained personnel and that's where the hold-up occurs,' he said.

 

'There's a large train of thought that one of the best ways of dealing with avian influenza is by detection and containment.

 

'We haven't had an influenza pandemic for a long time and there's a real possibility that we are due one. There's a strong feeling that H5N1 could be the next pandemic.

 

'It's jumped the species barrier - it's gone from killing birds to killing humans and it has an extremely high fatality rate.

 

 

'If it were able to jump from human to human it would become a potentially massive pandemic.

 

'The ability to detect and type the influenza virus immediately is essential in setting up controls as quickly as possible to minimise the spread of any potential pandemic virus.'

 

The £2.3 million project, known as Portfastflu, is being funded by the European Union.

 

Work on the project started in January at the university, where Dr McNally and his team have been designing the tests which will be carried out.

 

They have now completed this research, which will be passed to a French company to design the machine itself. It is expected to be completed by December 2010.

 

The university said tens of millions of birds have died or been slaughtered as a result of bird flu, while the H5N1 strain has officially claimed 243 lives from 385 confirmed cases.

Sun Aug 17, 3:29 AM ET

SEOUL, South Korea - South Korea plans to declare itself free of bird flu this week, more than three months after a series of outbreaks led authorities to slaughter nearly 8.5 million birds, an official said Sunday. A woman stands next to a poultry cage at a market in Denpasar on Bali island.(AFP/File/Sonny Tumbelaka) (BIRD FLU) (SOUTH KOREA)

 

South Korea to declare itself free of bird flu

 

Sun Aug 17, 3:29 AM ET

 

SEOUL, South Korea - South Korea plans to declare itself free of bird flu this week, more than three months after a series of outbreaks led authorities to slaughter nearly 8.5 million birds, an official said Sunday.

 

Kim Chang-seob, the Agriculture Ministry's chief veterinary officer, said the declaration will be reported Monday to the Paris-based animal health organization known as OIE.

 

The OIE has been at the forefront of global efforts to monitor and fight the H5N1 strain of bird flu, which scientists have tracked because they fear it may mutate into a human flu virus that starts a pandemic that could kill millions.

 

Under the OIE's regulations, a country can officially declare itself free of the disease if no new cases of bird flu have been found for three months.

 

In early April, South Korea confirmed its first outbreak of H5N1 in more than a year and the disease swept through the southern parts of the country.

 

But no new outbreak has been found since May 12, according to the ministry.

 

Bird flu also hit South Korea in 2003 and 2006, with authorities slaughtering millions of chickens, ducks and other poultry in response.

Sun Aug 17, 7:35 AM ET

Scientists in Uganda and their colleagues elsewhere are worried that human beings could contract a new strain of bird flu. Ugandan and French scientists have for months been observing the behaviour of a group of chimpanzees whose uncanny aptitude for self-medication could help their human cousins discover new drugs. (BIRD FLU) (HUMAN BIRD FLU) (BIRD FLU STRAINS) (UGANDA)

 

Uganda: New Strain of Bird Flu Poses a Major Threat

 

Sun Aug 17, 7:35 AM ET

 

Scientists in Uganda and their colleagues elsewhere are worried that human beings could contract a new strain of bird flu.

 

The acting World Health Organisation (WHO) Representative in Uganda, Dr Jean Baptiste Tapko, said a global state of alert to the pandemic influenza has been declared.

 

"Transmission of the influenza virus infection to humans has been mainly from infected birds," Dr Tapko said. He was addressing a Kampala symposium that is drafting a code of ethics for pandemic influenza detection and response in Africa.

 

Dr Tapko said the emergence of H5NI strain of influenza virus would mark the beginning of an influenza pandemic.

 

In 1918, an influenza pandemic caused up to 50 million deaths worldwide while in 1957 influenza claimed between one to two million lives. In 1968 the pandemic caused about 700,000 deaths worldwide

 

Dr Tapko said that since 2003, a total of 385 human cases and 243 deaths from infection with avian influenza sub-type H5NI had been reported in 15 countries three of which are in Africa including Nigeria and Egypt.

 

"Unlike the previous pandemics, we have had the opportunity to see this one unfolding. We are all expected to be better prepared to rapidly contain and mitigate the possible impact of the pandemic," he said.

 

Dr Tapko said several countries including Uganda have developed and are implementing national multi-sectoral preparedness plans.

 

 

The potential public health impact of an influenza pandemic is enormous including social and economic disruptions , travel and trade restrictions, that would result into massive economic loses, overburdening health care services that are already weak in most developing countries.

 

Health Minister, Dr Stephen Mallinga said there are high chances for the virus to mutate (change ) and result into a serious influenza pandemic.

 

An influenza pandemic occurs when a new influenza virus emerges for which there is little or no immunity in the human population and as a result, infected human beings start to infect others.

 

by Jane Nafula, Kampala

AllAfrica.com - Aug 17 1:21 AM

Sun Aug 17, 2:08 PM ET

WASHINGTON (Reuters) - Antibodies from survivors of the 1918 flu pandemic, the worst in human memory, still protect against the highly deadly virus, researchers reported on Sunday. (BIRD FLU) ( Medical News)

 

Antibodies still protect 1918 flu survivors: study

 

Sun Aug 17, 2:08 PM ET

 

WASHINGTON (Reuters) - Antibodies from survivors of the 1918 flu pandemic, the worst in human memory, still protect against the highly deadly virus, researchers reported on Sunday.

 

The findings by a team of influenza and immune system experts suggest new and better ways to fight viruses, especially new pandemic strains that emerge and spread before a vaccine can be formulated.

 

These survivors, now aged 91 to 101, all lived through the pandemic as children.

 

Their immune systems still carry a memory of that virus and can produce proteins called antibodies that kill the 1918 flu strain with surprising efficiency, the researchers report in the journal Nature.

 

"It was very surprising that these subjects would still have cells floating in their blood so long afterward," said Dr. James Crowe of Vanderbilt University in Tennessee, who helped lead the study.

 

The antibodies also protected mice from the 1918 virus, which swept around the world at the end of World War One killing between 50 million and 100 million people, Crowe's team reports in the journal Nature.

 

"The antibodies that we isolated are remarkable antibodies. They grab onto the virus very tightly and they virtually never fall off," Crowe said in a telephone interview.

 

"That allows them to kill the 1918 virus with extreme potency, meaning it takes a very small amount of antibody."

 

The human body has two systems for fighting off bacterial and viral invaders. One system uses so-called T-cells while the other employs B-cells, made in the bone marrow, which in turn make antibodies to both flag and directly attack the targets.

 

RESURRECTED VIRUS

 

Dr. Christopher Basler and colleagues at the Mount Sinai School of Medicine in New York tested the 1918 survivors and found that in most of them, the B-cells made antibodies highly attuned to the 1918 flu strain.

 

Dr. Terrence Tumpey at the U.S. Centers for Disease Control and Prevention had worked on a team that resurrected the 1918 virus taken from buried victims of the epidemic and tested this virus in mice. Mice given the antibodies from the elderly survivors lived, while those given placebos died.

 

Crowe said it will now be important to test other people who have had influenza to see if their immune responses are as strong. "The thought is the first influenza that you see during life is the one that you have the best immunity to," he said.

 

"If we can learn the rules about how these antibodies work we may be able to design antibodies to lots of other viruses."

 

The 1918 flu was an H1N1 strain that apparently came straight from birds. "This study tells us that human beings can make long lasting immune responses to bird influenza," Crowe said.

 

Crowe said his team is working to get antibodies from people vaccinated with experimental shots for the H5N1 avian influenza now circulating in Asia, Europe, the Middle East and Africa. H5N1 mostly affects birds but it has infected 385 people since 2003, killing 243.

 

Experts fear that, like the H1N1 virus did in 1918, H5N1 will mutate into a form that passes easily among people and spark another pandemic. No one knows if the vaccines being made now would protect against whatever form of H5N1 might emerge.

 

Crowe said antibodies from survivors might make a good interim treatment while a vaccine is formulated, manufactured and distributed -- a process that would take months.

 

By Maggie Fox, Health and Science Editor

(Editing by Cynthia Osterman)

Mon Aug 18, 11:34 AM ET

WASHINGTON - Nearly a century after history's most lethal flu faded away, survivors' bloodstreams still carry super-potent protection against the 1918 virus, demonstrating the remarkable durability of the human immune system. (BIRD FLU) (Medical News)

 

Secrets of killer 1918 flu confirm immunity theory

 

Mon Aug 18, 11:34 AM ET

 

WASHINGTON - Nearly a century after history's most lethal flu faded away, survivors' bloodstreams still carry super-potent protection against the 1918 virus, demonstrating the remarkable durability of the human immune system.

 

Scientists tested the blood of 32 people aged 92 to 102 who were exposed to the 1918 pandemic flu and found antibodies for the old flu strain.

 

Researchers then made a vaccine that kept alive all the mice infected with the killer flu, according to a study published online Sunday in Nature.

 

Their research confirms theories that the human immune system has a steel-trap memory.

 

"What doesn't kill you, makes you stronger," said study co-author Eric Altschuler of the University of Medicine and Dentistry in New Jersey.

 

But these antibodies also have mutated, making them more potent, said James Crowe, the study's lead author and a professor of microbiology and immunology at Vanderbilt University Medical Center in Tennessee.

 

Crowe hopes to boost potencies of vaccines against newer bird flu strains.

 

By SETH BORENSTEIN, The Associated Press

 

Fri Aug 29, 8:52 PM ET

Scientists funded by the Wellcome Trust are to examine what is preventing the H5N1 avian influenza virus from causing a human pandemic and what mutations are required to realise its deadly potential. The research could hold the key to early identification of a potential influenza pandemic, and to developing drugs and a vaccine.(BIRD FLU) (VACCINES) (HUMAN BIRD FLU VACCINE) (HUMAN BIRD FLU) (RESEARCH)

 

Scientists examine bird flu infections to monitor for 'pandemic' mutations

 

Fri Aug 29, 8:52 PM ET

 

Scientists funded by the Wellcome Trust are to examine what is preventing the H5N1 avian influenza virus from causing a human pandemic and what mutations are required to realise its deadly potential. The research could hold the key to early identification of a potential influenza pandemic, and to developing drugs and a vaccine.

 

Since its reappearance in 1997, the H5N1 influenza virus has caused disease and death in millions of birds around the globe. The number of infections in humans is still relatively small, however: from 2003 to the end of June 2008 there had been 385 known cases in humans, 243 of them fatal (1). So far, there appear to have been very few cases of human-to-human transmission.

 

Professor Ten Feizi at Imperial College London believes one reason why H5N1 has not yet evolved into an effective pathogen capable of widespread transmission between humans lies in how the virus attaches itself to the respiratory tract. She is leading an international research project which has received over £720,000 from the Wellcome Trust to identify the receptor molecules in the human respiratory tract to which viruses attach and to look at how changes in the binding protein on the surface of the virus might increase its ability to attach to the tract and cause infection.

 

Professor Feizi will work with Professors Menno de Jong and Jeremy Farrar from the Wellcome Trust's South East Asia Programme in Vietnam, Dr Alan Hay and Dr Steve Gamblin at the Medical Research Council National Institute for Medical Research, London, and Dr Mikhail Matrosovich at the Philipps University of Marburg, Germany.

 

"Over the last few years particularly in Asia we have seen just how deadly the H5N1 virus can be," says Professor Farrar from the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam, where a number of people have been treated for infection by the virus. "So far, we have been relatively fortunate and there has been only limited evidence of the virus transmitting from human to human. The more we understand about the virus, how it interacts with the body, the better we will be prepared for any serious mutations that may arise."

 

In humans, influenza infection occurs via the respiratory tract, or airway. In order to cause disease, the virus must enter the body's cells where it can replicate and spread, but it must first find a site to which it can attach, known as a receptor. The virus can only attach to and enter the cells if the receptor fits into the binding proteins, or haemagglutinins (the "H" in H5N1), on the surface of the virus.

 

Previous research has shown that the haemagglutinin on H5N1 favours a particular form of receptor known as a "2,3 receptor". These are abundant on cells of birds, but in humans are found mostly on cells of the lower respiratory tract (the lungs). Professor Feizi and colleagues have shown that mucus in the upper airway in humans also contains 2,3 receptors, but here the mucus acts as a defence mechanism to which the virus binds, blocking its progress and enabling the body to "sweep out" the virus. Both factors suggest that huge doses of the virus are required in order to infect humans, a theory supported by evidence that those who have become infected have spent large amounts of time in close proximity to infected fowl.

 

As with all viruses, H5N1 is continually mutating, and it is changes that allow the virus to attach to "2,6 receptors" in the human upper airway which may enable the virus to become more infectious to humans.

 

"If the bird flu virus evolves t